產(chǎn)品詳情
簡單介紹:
AKR1C3InhibitorI
詳情介紹:
Purpose | A highly potent and selective inhibitor of the type 5 17-beta-hydroxysteroid dehydrogenase AKR1C3. |
Characteristics | In repeat assays it showed an IC50of 0.013 ± 0.003 μM for AKR1C3, compared with 20.3 ± 3.8 μM against AKR1C1 and > 30 μM against AKR1C2 and AKR1C4. This inhibitor also showed displays potency in a cellular assay, blocking the ability of AKR1C3 to metabolize a proven substrate. |
Purity | ≥ 98?% by HPLC |
Chemical Name | 3-(3,4-Dihydroisoquinolin2(1H)-ylsulfonyl)benzoic acid |
Formula | C??H??NO?S |
Permeability | Cell-permeable |
Solubility | DMSO |
Molecular Weight | 317.36 g/mol |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from air and light |
Storage | -20 °C |
Expiry Date | 36 months |
Supplier Images |
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